Endocrine Abstracts

Graves’ disease (GD) and gestational transient thyrotoxicosis (GTT) are the main causes of hyperthyroidism in pregnancy, their prevalence ranging between 0.1–0.4% and 0.3–11%, respectively.Aim of the study: To evaluate both prevalence and outcome of gestational hyperthyroidism in mild to moderate ID areas.Subjects and methods: 482 consecutive pregnant women who had never undergone thyroid function evaluation before a...

The prevalence of differentiated thyroid carcinoma (DTC) in lingual thyroid (LT) and thyroglossal duct cysts (TDC) is around 1%. Nowadays, almost 200 cases of DTC were reported in TDC and <60 cases in LT. Here we report four cases of neoplasia in LT (1/4) and TDC (3/4) in a consecutive series of 950 DTC patients (0.4%).Case 1: D.F. 63 year-old woman with thyroid follicular carcinoma in ectopic gland located at her tongue’s basis. March 2009: the...

Autoimmune hypothyroidism due to thyroid stimulation blocking antibodies (TSB-Ab) is uncommon. When occurring in pregnancy, this condition may be responsible for feto-neonatal complications as a result of both maternal hypothyroidism and trans-placental TSB-Ab transfer to the fetus.Clinical case: September 2010: a 27 year-old woman was diagnosed with autoimmune severe hypothyroidism (TSH 325 mIU/l (n.v 0.4–4.0), FT4 1.54 pmol/l (n.v. 11.5...